منابع مشابه
MOLECULAR ANALYSIS OF THE SULFUR REGULATORY CIRCUIT OF NEUROSPORA CRASSA
The sulfur regulatory circuit of the filamentous fungus, Neurospora crassa, consists of a set of unlinked structural genes which encode sulfur catabolic and two major regulatory genes which govern their expression. The cys-3 regulatory gene encode a transacting regulatory protein which activates the expression of cys-14 and ars, whereas the other regulatory genes Scon-l and Scon-2 appear to...
متن کاملmolecular analysis of the sulfur regulatory circuit of neurospora crassa
the sulfur regulatory circuit of the filamentous fungus, neurospora crassa, consists of a set of unlinked structural genes which encode sulfur catabolic and two major regulatory genes which govern their expression. the cys-3 regulatory gene encode a transacting regulatory protein which activates the expression of cys-14 and ars, whereas the other regulatory genes scon-l and scon-2 appear to act...
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Analysis of synthetic gene regulatory circuits can provide insight into circuit behavior and evolution. An alternative approach is to modify a naturally occurring circuit, by using genetic methods to select functional circuits and evolve their properties. We have applied this approach to the circuitry of phage . This phage grows lytically, forms stable lysogens, and can switch from this regulat...
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miRNAs (microRNAs) are a class of endogenous small RNAs that are thought to negatively regulate protein production. Aberrant expression of many miRNAs is linked to cancer and other diseases. Little is known about the factors that regulate the expression of miRNAs. We have identified numerous regulatory elements upstream of miRNA genes that are likely to be essential to the transcriptional and p...
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How can cells shape and utilize dynamic gene regulation to enable complex cellular behaviors? I study this question in natural and a synthetic context. The first project studies how a natural genetic network can imbue cells with a sense of ‘time’. It has long been known that environmental signals induce diverse cellular di↵erentiation programs. In certain systems, cells defer di↵erentiation for...
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ژورنال
عنوان ژورنال: Nature Reviews Immunology
سال: 2006
ISSN: 1474-1733,1474-1741
DOI: 10.1038/nri1876